Abstract: Certain mAbs, bispecific antibodies (bsAbs) and Fc-fusion proteins are prone to form aggregates in cell culture. We previously showed that in these cases large aggregates do not bind to Protein A resin as their sizes prevent them from entering the pores of resin beads, leading to reduced step yield....
Keywords: Aggregate; Bispecific antibody (bsAb); Fc-fusion; Low pH; mAb; Protein A membrane; Protein A resin
Special Issue Article “Extraction Chromatography”
Abstract: Here we discuss our experiences with various approaches for measuring total Hg concentrations and speciation of Hg in environmental matrices. First, what Hg concentrations the method needs to measure should be considered as low Hg concentrations in samples will require pre-concentration before ICPMS analyses...
Keywords: ICPMS; Mercury; Isotopes of mercury
Special Issue Article “High-Performance Thin-Layer Chromatography”
Abstract: An optimized extraction procedure followed by a validated High–Performance Thin–Layer Chromatography (HPTLC) was applied for the assay of chlorpyrifos (CPF) levels in postmortem blood obtained in seven fatal intoxication cases...
Keywords: Liquid–liquid extraction; Whole blood; Chlorpyrifos; High–performance thin–layer; Chromatography; Validation
Special Issue Article “Gas Chromatography”
Abstract: In their paper published in the Journal of Chemical Engineering Data, Ugraskan, et al. made several inaccuracies in the determination of the surface properties of sodium alginate by using the Inverse Gas Chromatography (IGC) technique...
Keywords: Dispersive component of surface; Energy of solid; Specific enthalpy of adsorption; Acid base constant in lewis terms; Inverse gas chromatography
Copyright © 2016 Scientific Literature. All Rights Reserved.
Design by Scientific Literature