Special Issue Article “Cholestasis”

Increased Activity of Alkaline Phosphatase in COVID-19: Potential Mechanisms

Jinendra Satiya, Joanna M Lenik and Nora V Bergasa*

Abstract: Clinical manifestations of Coronavirus disease 2019 (COVID-19) are multisystemic and associated with a wide range of laboratory abnormalities. Abnormalities in serum liver profile are common, however, increased serum activity of alkaline phosphatase has not been frequently reported. Two cases of PCR confirmed Sars-CoV-2 infection and high alkaline...
Keywords: COVID-19; Alkaline phosphatase; Cholestasis; Interleukin-6

Special Issue Article “Cholangiocarcinoma”

Major Hepatopancreatoduodenectomy for Multifocal Cholangiocarcinoma of the Intrahepatic, Proximal, and Distal Bile Duct

Lendoire J*, Kohan G, Duek F, García de Dávila MT and Imventarza O

Abstract: A 58-year-old female patient presented in the outpatient clinic with obstructive jaundice that had lasted over one month. Her past medical history includes cholelithiasis treated by sphincterotomy, lithotripsy and stone extraction followed by a laparoscopic cholecystectomy 5 months ago.
Keywords: Multifocal Cholangiocarcinoma; Hepatopancreatoduodenectomy

Atypical Complications of Anti-Reflux Surgery; Post-Surgical Paraesophageal Hematoma: Two Case Reports

Mohamed Hassin Mohamed Chairi*, Jennifer Triguero Cabrera, Mónica Mogollón González, Cristina Plata Illescas, María Jesús Álvarez Martín and Jesús María Villar del Moral

Abstract: Paraesophageal hematoma; Hiatal hernia; Antireflux surgery...
Keywords: The laparoscopic approach is the current standard for the surgical treatment of gastroesophageal reflux disease refractory to medical treatment and symptomatic hiatal hernia. Although it is a safe surgery, its potential complications are frequently underestimated