clinicalneurology@scientificliterature.org
ABSTRACT
Facial motoneurons express an ion channel-type gamma-aminobutyric acid receptor (GABAAR) that is constructed from five subunits, including , and subunits. The transection of rat facial nerve was reported to lead to a significant downregulation of the GABAAR1 subunit. In this study, we investigated a transition of GABAAR2,3 and GABAAR1 subunits in axotomized (i.e., injured) rat facial nucleus. Immunoblotting
indicated that the levels of GABAAR1 significantly decreased in axotomized facial
nucleus from 3 days to 5 weeks post-injury.
Keywords:
Facial nerve, Axotomy, GABAA receptor
ABSTRACT
Post-traumatic leptomeningeal cyst is an uncommon neurosurgical condition that may complicates skull fracture. We managed a 10-year old boy who presented with a focal seizure involving left upper limb with secondary generalisation three months prior to presentation. He has associated gradually progressing right parietal scalp swelling. Physical examination revealed conscious child, oriented in time, place and
person with Glasgow coma score of fifteen. Pupils were 3mm and reacted normally to light, no cranial palsy, motor and sensory functions were intact in all limbs.
Keywords:
Leptomeningeal, Craniectomy, Duroplasty, Cranioplasty
ABSTRACT
Objective: Complete surgical extirpation of pilocytic astrocytoma is usually curative, however when these tumors are critical deeply-seated gross total resection is usually not feasible and ill-advised because of the high morbidities. The objective of this study is to evaluate the outcomes of Gamma Knife Surgery in the management of critical deep-seated postoperative residual partially cystic pilocytic astrocytoma <3cm in maximum diameter targeting the solid mural nodule.
Keywords:
Astrocytoma, Gamma knife surgery, Pilocytic astrocytoma, Stereotactic radiosurgery
ABSTRACT
Today it is known that the enhanced brain opioid system activity represent the major neurochemical variation occurring in stress conditions. Moreover, it has been shown that a chronic opioid hyperactivation may suppress the anticancer immunity, and promote cancer development.
Keywords:
Cannabinoid system, Melatonin, Neuroimmunomodulation, Opioid system, Pineal gland, Stress
ABSTRACT
Personality is referred to the individualist characteristics of a person which differentiate him from others. The deviant reflections of these characteristics lead to personality disorders. The current study intended to measure gender-based differences in personality disorders. The sample included 332 participants (188 men and 144 women).
Keywords:
Personality disorders, Gender
ABSTRACT
Introduction: Heart diseases are considered among the most frequent congenital
malformations; they have a great impact on pediatric morbidity and mortality.
Children with congenital heart disease present motor and neurocognitive deficits, as
well as specific functions such as attention and executive functions can be affected.
Keywords:
Cardiac surgery, Heart disease, Neurodevelopment, Pediatrics
ABSTRACT
A physiological phenomenon named movement-related sensory gating has been described in the literature in the late 80s. To the best of our knowledge, it has not yet been exploited in the BCI domain. We consider that this phenomenon could significantly decrease the resonance-like frequency of Steady State Somatosensory Evoked Potentials (SSSEP) and be exploited as a voluntary command of the user will.
Keywords:
BCI; SSSEP; Movement-related sensory gating; Resonance-like frequency; Fibration; Steady state somatosensory evoked; potential
ABSTRACT
Background: Titanium (TC) or polyetheretherketone (PEEK) cages are acceptable grafts for Anterior Cervical Discectomy and Fusion (ACDF), restoring disc space height,
relieving cord compression, and providing enlargement of previously stenotic neural foramina. Here, we compared the clinical and radiological, outcomes and
complications utilizing TC vs. PEEK cages for Degenerative Cervical Disc Disease (DCDD).
Keywords:
Titanium cage, PEEK cage, ACDF and Degenerative Cervical Disc, Disease (DCDD)
Special Issue Article “Convulsions Causes and Treatment”
Abstract: Acute Intermittent Porphyria (AIP) is an autosomal dominant disorder due to the gene mutations in Porphobilinogen Deaminase (PBG), also called hydroxymethylbilane synthase. This enzymatic deficiency leads to the marked accumulation of the porphyrin...
Keywords: Acute intermittent porphyria; Guillain-Barré syndrome; Abdominal pain; Neuropsychiatric manifestations; Non-convulsive epileptic seizures