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LETTER
Since some decade’s frog’s secretion are also recognized as an important source of
new drugs, such as analgesics and antibiotics. We will review a series of bioactive
peptides from two different frog species, with a special focus on the potential use of
these peptides for the treatment of chronic pain.
Keywords:
Dermorphin, Cerulein, Cerulitide, Bombesin, Prokineticin, Bombina variegate, Phyllomedusa bicolor
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ABSTRACT
This paper shows the Wnt pathways, which are related to type 2 diabetes mellitus. Two main Wnt pathways have been described, canonical pathway and noncanonical pathway. Canonical pathway is related to a protein called β-catenin. In presence of Wnt, β-catenin is accumulated in cytoplasm and can be transported to nucleus to produce activation of gene transcription through TCF/LEF.
Keywords:
Wnt pathways; Diabetes; IDDM
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