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ABSTRACT
Facial motoneurons express an ion channel-type gamma-aminobutyric acid receptor (GABAAR) that is constructed from five subunits, including , and subunits. The transection of rat facial nerve was reported to lead to a significant downregulation of the GABAAR1 subunit. In this study, we investigated a transition of GABAAR2,3 and GABAAR1 subunits in axotomized (i.e., injured) rat facial nucleus. Immunoblotting
indicated that the levels of GABAAR1 significantly decreased in axotomized facial
nucleus from 3 days to 5 weeks post-injury.
Keywords:
Facial nerve, Axotomy, GABAA receptor
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ABSTRACT
Post-traumatic leptomeningeal cyst is an uncommon neurosurgical condition that may complicates skull fracture. We managed a 10-year old boy who presented with a focal seizure involving left upper limb with secondary generalisation three months prior to presentation. He has associated gradually progressing right parietal scalp swelling. Physical examination revealed conscious child, oriented in time, place and
person with Glasgow coma score of fifteen. Pupils were 3mm and reacted normally to light, no cranial palsy, motor and sensory functions were intact in all limbs.
Keywords:
Leptomeningeal, Craniectomy, Duroplasty, Cranioplasty
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ABSTRACT
Objective: Complete surgical extirpation of pilocytic astrocytoma is usually curative, however when these tumors are critical deeply-seated gross total resection is usually not feasible and ill-advised because of the high morbidities. The objective of this study is to evaluate the outcomes of Gamma Knife Surgery in the management of critical deep-seated postoperative residual partially cystic pilocytic astrocytoma <3cm in maximum diameter targeting the solid mural nodule.
Keywords:
Astrocytoma, Gamma knife surgery, Pilocytic astrocytoma, Stereotactic radiosurgery
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ABSTRACT
Today it is known that the enhanced brain opioid system activity represent the major neurochemical variation occurring in stress conditions. Moreover, it has been shown that a chronic opioid hyperactivation may suppress the anticancer immunity, and promote cancer development.
Keywords:
Cannabinoid system, Melatonin, Neuroimmunomodulation, Opioid system, Pineal gland, Stress
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ABSTRACT
Personality is referred to the individualist characteristics of a person which differentiate him from others. The deviant reflections of these characteristics lead to personality disorders. The current study intended to measure gender-based differences in personality disorders. The sample included 332 participants (188 men and 144 women).
Keywords:
Personality disorders, Gender
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ABSTRACT
Introduction: Heart diseases are considered among the most frequent congenital
malformations; they have a great impact on pediatric morbidity and mortality.
Children with congenital heart disease present motor and neurocognitive deficits, as
well as specific functions such as attention and executive functions can be affected.
Keywords:
Cardiac surgery, Heart disease, Neurodevelopment, Pediatrics
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